In November, 2013, the University of Maryland School of Medicine launched (dedicated) the Center for Innovative Biomedical Resources (CIBR), the administrative home for the UMSOM biomedical core resources. CIBR serve(s) as a center of excellence for state-of-the-art technologies, high-tech instrumentation, and expertise that supports biomedical research, clinical practice and health care in the state of Maryland and the region. Renovation of nearly 30,000 square feet of space was accomplished with $7.3 M in funding from an NIH grant (1G20RR030969, Reece, PI), made possible through the American Recovery and Reinvestment Act. Newly renovated space allows physical consolidation of many core facilities in common space, creating a dynamic environment that will enhance and stimulate high impact research through a trans-disciplinary approach. New facilities give faculty greater access to sophisticated instrumentation, as well as highly-trained technical staff who can offer support to faculty on experimental design, data analysis and interpretation, and provide training opportunities for graduate and medical students, postdoctoral fellows, and faculty within the University and its collaborators.